癌症中的大魔王是肺癌,每年奪去10000條人命,相當於總癌症死亡人數的1/5。
我們可以將肺癌分類,
★ 依照細胞類型區分
肺癌:
- 小細胞肺上皮細胞癌 Small cell lung carcinoma (SCLC)
- 非小細胞癌 Non-Small cell lung cancer (NSCLC)
- 肺腺癌 Lung adenocarcinoma (ADC)
- 鱗狀上皮細胞癌 Squamous cell carcinoma (SQCC)
- 大細胞上皮癌 Large cell carcinoma (LCC)
- 大細胞神經內分泌上皮癌 Large cell neuroendocrine carcinoma (LCNEC)
- 神經內分泌類上皮癌 Neuroendocrine carcinoid cancer (NECC)
非肺癌,源自於肋膜:
- 惡性間皮瘤 Malignant mesothelioma (Sarcoma)
★ 依照發生率分類(記:3開頭 – 2開頭 – 1開頭)
- Adenocarcinoma (38%)
- Squamous cell carcinoma (20%)
- Small cell carcinoma (14%)
- Large cell carcinoma (3%)
- Neuroendocrine carcinoid cancer (5%)
(1) Central carcinoid (佔Carcinoid的60%)
(2) Peripheral carcinoid (佔Carcinoid的40%) - Malignant mesothelioma (5%)
組織學分類
(1) Epitheliod (60%)
(2) Sarcomatoid (20%)
(3) Mixed (20%) - Other (20%)
★ 依照癌症轉移(Metastasis)排行
- 50%:Metastasis to bronchial, trachea, mediastinal lymph nodes(屬於local extension)
- 50%:Adrenal(2-5屬於distant extension)(記:Paraneoplastic syndrome中常有ACTH過盛)
- 30-50%:Liver
- 20%:Brain (記: 癌症造成腦病變)
- 20%:Bone
結論(這張表要背起來喔!國考愛考)
參考資料
1. UpToDate
2. Robbins Basic Pathology (2018)
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